Figure 5.

Effect of sulforaphane (SFN, 0.25 mg/kg/day) treatment on acetylcholine-induced relaxations of isolated aortic rings in high cholesterol diet (HCD)-fed rabbits. Values are expressed as means ± SEM, n = 5 in each group. Cumulative dose-response curves to acetylcholine (10⁻⁷–10⁻⁵M) were measured after precontraction with 1 µM phenylephrine. P < 0.05 for E_max value compared with control group (*) and compared with HCD group (#). One-way ANOVA followed by Tukey–Kramer’s multiple comparisons post hoc test