Figure 4.

SCE and SCF4 decreased the expression of pro-inflammatory mediators. (a) Protein expression of pro-inflammatory mediators iNOS and COX-2 by western blot analysis. (b) HO-1 expression was increased dose- and time-dependently following treatment with SCF4. Results of the western blot analysis represent three independent experiments that yielded similar results. Data are the means ± SEM (n = 3), *p < 0.05. COX-2: cyclooxygenase-2; HO-1: heme oxygenase-1; iNOS: inducible nitric oxide synthase; LPS: lipopolysaccharide; SCE: S. chinensis extract; SCF4: subfraction 4 of the n-hexane layer of the EtOH extract of the aerial parts of S. chinensis; SEM: standard error of the mean