Figure 6.

SCF4 activated NF-κB and Nrf2 signaling pathways. (a) Dose-dependent effects on protein expression of p65 and Nrf2 by western blot. (b) Time-dependent effects on protein expression of p65 and Nrf2 by western blot. Results of the western blot analysis represent three independent experiments that yielded similar results. Data are the means ± SEM (n = 3), *p < 0.05. NF-κB: nuclear factor kappa-light-chain-enhancer of activated B cells; Nrf2: nuclear factor erythroid 2-related factor 2; SCF4: subfraction 4 of the n-hexane layer of the EtOH extract of the aerial parts of S. chinensis; SEM: standard error of the mean