Experimental design. 0–4, previous exercise training in the D + PEx group (4 weeks); 4–5, induction of DM in the D + Se, D + Ex and D + PEx groups; 5–14, continuation of exercise training in the D + PEx group and initiation of exercise training in the D + Ex and C + Ex groups; 48h, sample collection of blood and urine 48h after the last training session, and euthanasia