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Positive ANF-immunostaining in heart of rat (A) SHR – very strong immunosignal in majority of atrial cardiomyocytes, (B) SHR with doxazosin treated – less numerous atrial muscle cells with ANF-immunoreactivity; (C) SHR – delicate ANF-reaction in some of ventricular cardiomyocytes; (D) SHR receiving doxazosin – single ventricular muscle cells with weak ANF-immunoreactivity. (A color version of this figure is available in the online journal.)
