Table II.
The effects of ECP on the expression of differentiation marker genes.
| Differentiation marker | Gene symbol | −CP
|
+CP
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 1 | Day 2 | Day 4 | Day 6 | Day 8 | Day 1 | Day 2 | Day 4 | Day 6 | Day 8 | ||
| Early phase | Cebpβ | 1.0 | 2.2 | 2.8 | 2.5 | 3.1 | 3.3 | 3.1 | 3.8 | 2.9 | 3.1 | 3.8 |
| Cebpδ | 1.0 | 1.0 | 1.0 | 1.2 | 2.6 | 1.0 | 0.9 | 0.9 | 1.4 | 1.9 | 1.1 | |
| Late phase | Cebpα | 1.0 | 1.3 | 3.0 | 4.2 | 8.7 | 5.9 | 1.3 | 3.2 | 4.9 | 6.5 | 8.8 |
| Pparγ | 1.0 | 1.0 | 2.1 | 12.0 | 11.2 | 9.9 | 1.0 | 4.5 | 9.7 | 10.8 | 13.2 | |
The expressions of Cebpβ and Cebpδ as early-differentiation markers and those of Cebpα and PPARγ as late-differentiation markers were determined by the microarray method. Each value is normalized to the value at day 0. ECP, extracts of chickpeas; Cebpβ, CCAAT-enhancer-binding proteins β; Pparγ, peroxisome proliferator-activated receptor γ.