Fig. 8.

Therapeutic regimen of TUDCA does not decrease HDM-induced airway fibrosis. A: representative images of α-SMA-stained lung tissue sections of vehicle-treated and TUDCA-treated HDM-challenged mice (×20 magnification; scale bars = 50 μm) and the quantification of percentage of area that positively stained for α-SMA immunostaining. Statistical differences were not significant between groups. B: measurement of collagen by hydroxyproline assay. Data are means ± SE of 6–8 mice/group. *P < 0.05 compared with their respective PBS controls. Statistical differences were not significant between vehicle-treated and TUDCA-treated HDM-challenged mice.