Table 2.
mRNA levels of ion transporters in the intestine
| Proximal Colon |
Distal Colon |
||||||
|---|---|---|---|---|---|---|---|
| Transporter | n | K8+/+ | K8+/− | K8−/− | K8+/+ | K8+/− | K8−/− |
| CFTR | 4 | 0.80 ± 0.11 | 1.10 ± 0.01* | 0.96 ± 0.05 | 1.30 ± 0.26 | 2.31 ± 0.41 | 1.56 ± 0.19 |
| NHE3 | 4 | 1.26 ± 0.15 | 1.07 ± 0.13 | 1.65 ± 0.19 | 1.23 ± 0.34 | 1.53 ± 0.39 | 1.70 ± 0.24 |
| PAT-1 | 4 | 1.11 ± 0.09 | 0.93 ± 0.01 | 0.73 ± 0.14 | ND | ND | ND |
| Cecum |
Ileum |
||||||
|---|---|---|---|---|---|---|---|
| Transporter | n | K8+/+ | K8+/− | K8−/− | K8+/+ | K8+/− | K8−/− |
| CFTR | 4 | 1.00 ± 0.07 | 0.93 ± 0.22 | 0.43 ± 0.12 | 0.84 ± 0.20 | 0.80 ± 0.15 | 1.00 ± 0.11 |
| NHE3 | 4 | 1.20 ± 0.26 | 1.30 ± 0.26 | 0.49 ± 0.20 | 1.07 ± 0.10 | 0.81 ± 0.12 | 0.70 ± 0.04 |
| PAT-1 | 4 | ND | ND | ND | 0.90 ± 0.10 | 1.20 ± 0.33 | 0.74 ± 0.12 |
Values are means ± SE.
*
P <0.05; ND, not determined.