Fig. 10.

Effect of coronary arterial pressure on coronary flow. A: metabolic rate M was matched to the data observed by Broten and Feigl (1) where coronary arterial pressure was set at 80 mmHg and 160 mmHg, with a pump. B: the model prediction (solid line) of the coronary flow as a function of coronary arterial pressure (P) plotted and compared to data (closed diamonds) from Broten and Feigl (1), measured in anesthetized animals under combined α-adrenergic, β-adrenergic and cholinergic (ACh) blockade. For this simulation the open-loop gain was set to zero with all other parameter values from Table 1.