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Time-of-day-dependent variations in slc5a6 gene expression in cardiomyocyte-specific BMAL1 knockout (CBK; A) and cardiomyocyte-specific CLOCK mutant (CCM; B) hearts, as well as littermate control hearts. Gene expression was assessed through microarray (i) and RT-PCR (ii) approaches. Hearts were isolated at 3-h intervals. Data are shown as mean ± SE for 6 separate observations/group.
