Table 4.

Genes involved in retinoid metabolism identified in microarray screen

	Right Ventricle		Left Ventricle
Gene	LRVAS vs. WTVAS	LRVAD vs. WTVAS	LRVAS vs. WTVAS	LRVAD vs. WTVAS
Dhrs3, a retinaldehyde reductase	−1.2 (0.02)	−1.5 (0.0004)	ns	ns
	FDR = 0.37	FDR = 0.37
Lrat, transfers ester to retinol	3.0 (7.9 e−7)	2.6 (1.6 e−6)	2.7 (5.3 e−7)	2.0 (3.9 e−6)
	FDR = 0.008	FDR = 0.008	FDR = 0.007	FDR = 0.007
Rbp7, cellular retinol binding protein III	1.7 (0.009)	2.3 (0.001)	ns	ns
	FDR = 0.56	FDR = 0.56

Values in unbolded font failed 1 of 3 parameters for significance but are included to show trends. Values represent significant fold changes in transcript expression relative to WTVAS control tissues.

ns, not significantly different than WTVAS; FDR, false discovery rate.