Table 3.
Microvascular function in patients with CF and control subjects
| Variable | Patients with CF | Control Subjects | P Value |
|---|---|---|---|
| Postocclusive reactive hyperemia | |||
| Baseline, PU | 42 ± 8 | 40 ± 5 | 0.748 |
| PeakPORH, PU | 167 ± 43 | 207 ± 22 | 0.187 |
| Relative changePORH, % | 518 ± 174 | 801 ± 125 | 0.039* |
| TTPPORH, s | 16 ± 6 | 15 ± 2 | 0.296 |
| Local thermal hyperemia | |||
| Baseline, PU | 36 ± 8 | 35 ± 6 | 0.676 |
| PeakLTH, PU | 302 ± 44 | 301 ± 51 | 0.275 |
| Relative changeLTH, % | 1,338 ± 436 | 1,574 ± 620 | 0.045* |
| TTPLTH, s | 781 ± 197 | 806 ± 182 | 0.113 |
| Iontophoresis with ACh | |||
| Baseline, PU | 40 ± 11 | 34 ± 11 | 0.083 |
| PeakACh, PU | 129 ± 54 | 122 ± 41 | 0.094 |
| Relative changeACh, % | 416 ± 140 | 617 ± 143 | 0.032* |
| TTPACh, s | 16 ± 6 | 15 ± 2 | 0.494 |
Values are means ± SD.
CF, cystic fibrosis; PORH, postocclusive reactive hyperemia; LTH, local thermal hyperemia; ACh, acetylcholine; TTP, time to peak; PU, perfusion units.
*
Statistically significant.