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. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: Int J Obes (Lond). 2016 Feb 15;40(7):1183–1186. doi: 10.1038/ijo.2016.31

Figure 1.

Figure 1

System (90mg/kg; IP) and central (10μg/5μl) NAC alters binge behavior produced by daily limited access to a palatable food. (A) NAC treated animals ate significantly less WD (30 min/day) compared to saline injected control animals. (B) Subsequently, NAC treated animals ate significantly more SC over the duration of the study. (C) Percent kilocalorie intake of SC on the 14th day is significantly higher for the NAC treated group, while WD consumption was significantly decreased compared to the control group. (D,E) There is no significant difference in cumulative food intake or body weight gained between the two experimental groups. (F) In a separate study, animals received infusions (NAC or saline; ICV) 30 minutes prior to accessing WD, central administration of NAC significantly suppressed WD consumption over the 7 day study. Data expressed as mean ± SEM. * = P < .05 compared to control group.