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. Author manuscript; available in PMC: 2017 Jul 15.
Published in final edited form as: J Immunol. 2016 Jun 13;197(2):458–469. doi: 10.4049/jimmunol.1502283

Figure 6. Pbx1-d Tg expression in CD4+ T cells increased affinity maturation of TH1-related isotypes.

Figure 6

B6 and Pbx1-d Tg mice were immunized with NP-KLH then boosted 2 and 6 weeks later (arrows on X axes). Serum levels of NP-specific Abs 1 wk before and after boosting measured in plates coated with NP4 (A) or NP25 (B) BSA. C. Affinity measured as the NP4 / NP25 ratio for each isotype, n = 5.