Figure 7. Pbx1-d Tg in CD4+ T cells increased the expression of miR-10a, miR-21, and miR-155.
miRNA expression was analyzed by qPCR in FOXP3+-GFP+ (A) and FOXP3-GFP− (B) CD4+ T cells from Pbx1-d Tg.Foxp3egfp, B6.Sle1a1.Foxp3egfp, and B6.Foxp3egfp spleens. Representative FACS plots for follicular T cells in spleens from 4 month old B6 and TC mice (C) and corresponding percentages and absolute numbers of TFH cells (D). E. miRNAs expression in CD4+ T cells from B6 and TC mice at 2, 4, and 10–12 month of age, n = 3–4.
