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. Author manuscript; available in PMC: 2017 Jul 5.
Published in final edited form as: Lab Chip. 2016 Jul 5;16(14):2551–2571. doi: 10.1039/c6lc00489j

Figure 4.

Figure 4

Microfluidic based myelin formation and axonal isolation. A, B) Schematic of microfluidic devices for myelination. C) Microfluidic myelinating oligodendrocytes (MBP), neurites (TUJ1) and cell nuclei (DAPI). Brackets mark indicates myelin, tubes of oligodendrocyte extensions wrapping neuritis. D) Arrowheads marked tubes showed by optical transverse sections (Scale bars: 20 μm in C and 3 μm in D) (Reproduced from Ref. 124. Copyright 2015 with permission from The Company of Biologists Ltd). E) Three-chamber microfluidic devices for Map5 stained axonal isolation of ESC_Ns (Reproduced from Ref. 116. Copyright 2015 with permission from Springer).