Figure 1. Visualization of thalamocortical functional connectivity segregation in neonates: cocaine + poly-drug (PCE), non-cocaine + poly-drug (NCOC), and healthy controls (CTR).
Functional connectivity is depicted on the surface model and pseudo-colored based on the Fisher Z-transformation of the temporal correlation (Z-Correlation, see color bar) with the seed regions (anterior – posterior thalamus). Thresholds were set using a combined approach (α < 0.05): voxel-wise p ≤ 0.01, minimum number of voxels = 32, third-nearest neighbor clustering (i.e. voxels cluster together if faces, or edges, or corners touch).