Table 4. Interaction between RMR and the UCP3 variant explains FI34 in female nonagenarians.
| rs591758 | rs675547 | rs1626521 | ||||
|---|---|---|---|---|---|---|
|
|
|
|
||||
| b | se | b | se | b | se | |
| RMR | 2.4e-4 | 1.4e-4 | 1.4e-4 | 1.6e-4 | -7.1e-5 | 1.5e-4 |
| SNP | 1.6e-2 | 0.11 | -9.4e-2 | 0.12 | -0.40 * | 0.16 |
| RMRxSNP | 2.6e-5 | 1.1e-4 | 1.2e-4 | 1.2e-4 | 3.9e-4 * | 1.6e-4 |
|
|
|
|
|
|||
| R2 | 0.32 | 0.24 | 0.25 | |||
| P | 0.0013 | 0.0066 | 0.0057 | |||
b = regression coefficient
p ≤ 0.05 and
p ≤ 0.01);
se = standard error of b; RMR = resting metabolic rate; SNP = additive genetic model for each SNP; R2= adjusted R2; P = p value of the coefficient of determination (R2) obtained by application of the F-statistic in analysis of variance; sample size (n = 37)