Table 6. Interaction between RMR and the UCP3 variant in female nonagenarians explains FI₃₄ after adjustment for muscle mass and physical activity.

	rs591758		rs675547		rs1626521
	b	se	b	se	b	se
FFM	-5.7e-3 **	2.1e-3	-5.4e-3 *	2.3e-3	-3.6e-3	2.3e-3
EESI	-9.7e-6 **	3.0e-6	-1.1e-5 **	3.1e-6	-1.2e-3 ***	2.9e-6
RMR	3.1e-4 *	1.5e-4	2.1e-4	1.7e-4	5.1e-6	1.5e-4
SNP	-6.5e-2	9.7e-2	-0.15	0.11	-0.41 **	0.13
RMRxSNP	1.0e-4	9.5e-5	1.8e-4	1.0e-4	4.1e-4 **	1.3e-4
R2	0.56		0.52		0.52
P	< 0.0001		< 0.0001		< 0.0001

b = regression coefficient

^*p ≤ 0.05,

^**p ≤ 0.01,

^***p ≤ 0.001);

se = standard error of b; FFM = fat-free mass; EESI= energy expenditure summary index in the Yale Physical Activity Survey; RMR = resting metabolic rate; SNP = additive genetic model for each SNP; R²= adjusted R²; P = p value of the coefficient of determination (R²) obtained by application of the F-statistic in analysis of variance; sample size (n = 37)