Table 3.
Numbers of Theileria parva antigen gene sequence alleles and total number of polymorphic residues present in allelic variants detected in the components of the Muguga cocktail vaccine (Kiambu 5, Serengeti and Muguga).
| Gene | Total number of sequence readsa | Polymorphic nucleotides | No. alleles (nucleotide level) | Polymorphic amino acids | No. alleles (amino acid level) |
|---|---|---|---|---|---|
| Tp1 | 6,156 | 0/393 | 1 | 0/131 | 1 |
| Tp2 | 1,596 | 2/290 | 2 | 2/96 | 2 |
| Tp3b | 7,196 | 16/366 | 3 | 7/110 | 3 |
| Tp4b | 4,314 | 41/382 | 4 | 0/40 | 1 |
| Tp5b | 16,214 | 4/308 | 2 | 0/62 | 1 |
| Tp6 | 4,263 | 10/291 | 3 | 0/96 | 1 |
| Tp7 | 13,356 | 7/253 | 2 | 1/84 | 2 |
| Tp8 | 11,364 | 0/262 | 1 | 0/87 | 1 |
| Tp10b | 12,360 | 3/277 | 2 | 1/59 | 2 |
a
The total of sequence reads for the Muguga cocktail is the sum of reads obtained for each of the individual stocks.
b
These genes contain introns, accounting for the discrepancies between nucleotide and amino acid lengths.