FIGURE 1.

Pho4 mediates the response to different stresses. (A) 10-fold cell dilutions of the indicated strains were spotted on YPD plates supplemented with indicated compounds. Plates were incubated at 37°C for 18 h. MD means menadione. (B) Liquid YPD cell suspensions were exposed to 0.6 mM GSNO, incubated at 37°C and samples collected at different time points. Cells were spread on SD plates and viable cells were count as CFUs. Relative viability was expressed as percentage of CFUs at different times per CFUs prior GSNO addition. Two-way ANOVA test was performed to evidence statistical differences.