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. 2016 Mar 28;27:320–331. doi: 10.1007/s00335-016-9628-9

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Cellular senescence and organismal aging. Although these processes involve different levels of complexity, evidence linking senescence and aging has been accumulating. Correlation between aging and senescence (Aging >Senescence), and some functional relevance of senescence for the aging process (Senescence >Aging) are shown. (Question mark) represents that the statement appears to be controversial (see text)