Table 3.

Univariate analysis of local control, locoregional control, disease-free survival, and overall survival for various patient, tumor, and treatment characteristics.

Characteristic	Univariate analysis*
	LC		LRC		DFS		OS
	HR (95% CI)	P Value	HR (95% CI)	P Value	HR (95% CI)	P Value	HR (95% CI)	P Value
Sex, male vs female	1.8 (0.2-16.0)	0.60	1.1 (0.3-4.1)	0.93	1.4 (0.4-4.3)	0.58	1.4 (0.4-5.5)	0.63
Age, >60 vs ≤60	3.4 (0.5-67.2)	0.22	3.5 (0.88-23.4)	0.08	3.7 (1.18-16.1	0.02	3.6 (0.9-23.7)	0.07
Size, >5 cm vs ≤5 cm	3.0 (0.5-23.1)	0.24	2.1 (0.6-7.5)	0.25	2.1 (0.8-5.7)	0.15	1.25 (0.32-4.4)	0.73
Histology
High vs low grade	0.6 (0.1-12.6)	0.71	1.0 (0.2-18.7)	0.99	0.85 (0.22-5.6)	0.80	0.66 (0.15-4.5)	0.62
Angio vs other	15.5 (2.3-306.5)	<0.005	17.7 (4.4-118.1)	<0.001	8.9 (3.2-28.5)	<0.001	4.5 (1.3-17.8)	0.02
Deep vs superficial	0.4 (0.05-2.3)	0.29	0.57 (0.16-2.1)	0.39	0.74 (0.28-2.1)	0.43	0.33 (0.08-1.2)	0.08
Presentation, recurrent vs. primary	1.3 (0.11-14.7)	0.80	0.62 (0.03-29.7)	0.63	1.2 (0.23-3.6)	0.78	1.0 (0.15-4.1)	0.99
RT
>60 Gy vs ≤60 Gy	3.3 (0.54-24.9)	0.19	2.6 (0.7-9.4)	0.14	2.4 (0.86-6.4)	0.09	2.3 (0.6-8.5)	0.19
Preoperative vs post-operative	0 (-)	0.30	0.63 (0.03-3.9)	0.66	0.66 (0.10-2.5)	0.57	0.56 (0.03-3.3)	0.57
Alone vs with surgery	28.2 (4.5-218.8)	<0.001	15.1 (3.8-53.8)	<0.001	6.9 (1.9-20.4)	0.006	6.1 (1.3-22.0)	0.03
IMRT vs 3-D RT	0.82 (0.14-6.2)	0.83	2.2 (0.55-14.7)	0.28	1.12 (0.4-3.6)	0.83	2.0 (0.45-13.6)	0.57
Elective nodal RT	0.93 (0.05-6.3)	0.95	0.92 (0.14-3.7)	0.92	0.87 (0.20-2.7)	0.82	1.3 (0.28-4.7)	0.72

Angio, angiosarcoma; DFS, disease-free survival; HR, hazard ratio; IMRT, intensity-modulated radiation therapy; Inf, infinite; LC, local control; LRC, locoregional control; OS, overall survival; RT, radiation therapy; 3-D, 3-dimensional.

*Boldface type indicates statistically significant data.