Table 4.
Summary of relevant prior studies with survival data and treatment with radiation therapy data.
| Institution, Country | Authors, year | Study dates | Patients, no. | Angio, % | Rhabdo, % | Med FU, y | Tx with RT, % | RT regimen | Median dose, Gy | LC or LRC, % (y) | DM, % (y) | DFS, % (y) | OS,) % (y) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGH, USA | Willers et al.,15 1995 | 1972-1993 | 57 | 19 | 0 | 4.3 | 100 | Preoperative, postoperative, definitive | 64.80 | LRC: 60(5) | 23(5) | NR | 66(5) |
| TMH, India | Dudhat et al.,5 2000 | 1981-1995 | 72 | 0 | 0 | NR | 53 | Postoperative | NR | NR | NR | 45(5) | 60(5) |
| University of Miami, USA | Chen et al.,19 2005 | 1996-2003 | 39 | 0 | 10 | 8.7 | 100 | Preoperative, postoperative, definitive | NR | 78(5) | 63(5) | ||
| University, of Florida USA | Trifiletti et al.,13 2012 | 1981-2009 | 24 | 0 | 0 | 11.1 | 100 | Postoperative | 64.80 | LC: 73(10) | 0(10) | 73(10) | 73(10) |
| IRCCS, Italy | Mattavelli et al.,9 2013 | 1990-2010 | 167 | 5 | 0 | 5.5 | 36 | Preoperative, postoperative | NR | LC: 81(10) | 11(10) | NR | NR |
| AMC, South Korea | Park et al.,17 2014 | 1995-2012 | 122 | 12 | 20 | 6 | 53 | Postoperative, definitive | 60.00 | LRC: 76(5), 64(10) | NR | NR | 75(5), 66(10) |
| NCCS, Singapore | Yeang et al.,16 2013 | 2002-2011 | 83 | 16 | 6 | 6.9 | 53 | Postoperative, definitive | NR | LRC: 49(5) | 29(5) | 37(5) | 45(5) |
| University of Washington, USA | Chang,18 2014 | 2000-2012 | 97 | 23 | 11 | 1.8 | 55 | Preoperative, Postoperative, Definitive | NR | NR | NR | NR | 78(5) |
| Present study | Vitzthum et al. | 1998-2012 | 48 | 29 | 2 | 4.8 | 100 | Preoperative, postoperative, definitive | 60.00 | LC: 87(5) LRC: 73(5) | 16(5) | 63(5) | 83(5) |
AMC, Asan Medical Center; Angio, angiosarcoma; DM, distant metastasis; DFS, disease-free survival; IRCCS, Fondazione Instituto Nazionale del Tumori; LC, local control; LRC, locoregional control; Med FU, median follow-up; MGH, Massachusetts General Hospital; NCCS, National Cancer Centre Singapore; NR, not reported; OS, overall survival; Rhabdo, rhabdomyosarcoma; RT, radiation therapy; TMH, Tata Memorial Hospital; Tx with RT, treatment (or treated) with radiation therapy.