Table 1. Summary of the study participants utilised in the exome sequencing and in the association analysis.

	Exome sequencing		Association analysis
	PE cases	Scoliosis reference for filtering*	PE cases	Non-PE controls	SISu reference
Sample size	100	100	1353	699	6118
Female%	100%	76%	100%	100%	57%
Ancestry	Finnish	Swedish	Finnish	Finnish	Finnish

^*Swedish scoliosis patients that were pooled and exome sequenced with the same method as the pre-eclamptic cases. These controls were utilised as a technical control to filter out false positive and common variants. PE = pre-eclampsia; SISu = Sequencing Initiative Suomi.