Table 5. Pooled estimates of Mortality analyses in subgroups.
Sources | No. of studies | Pooled estimates |
Tests of heterogeneity |
Tests of publication bias |
|||
---|---|---|---|---|---|---|---|
HR | 95%CI | I2(%) | p-val. | Begg’s p-val. | Egger’s p-val. | ||
PCa-specific mortality | 8 | 0.68 | 0.56–0.80 | 77.2 | <0.001 | 0.386 | 0.063 |
Exclude Serruys et al. | 7 | 0.68 | 0.55–0.80 | 80.5 | <0.001 | 0.072 | 0.018 |
Age | |||||||
Adjusted | 5 | 0.64 | 0.48–0.79 | 87.0 | <0.001 | 0.086 | 0.004 |
Not adjusted | 2 | 0.78 | 0.60–0.97 | 0.0 | 0.908 | – | – |
BMI | |||||||
Adjusted | 2 | 0.62 | 0.32–0.92 | 84.8 | 0.010 | – | – |
Not adjusted | 5 | 0.68 | 0.50–0.85 | 82.0 | <0.001 | 0.806 | 0.258 |
PSA | |||||||
Adjusted | 3 | 0.61 | 0.35–0.86 | 89.4 | <0.001 | 1.000 | 0.077 |
Not adjusted | 4 | 0.70 | 0.51–0.89 | 70.9 | 0.016 | 0.734 | 0.445 |
BMI & Age | |||||||
Adjusted | 2 | 0.62 | 0.32–0.92 | 84.8 | 0.010 | – | – |
Not adjusted | 5 | 0.68 | 0.50–0.85 | 82.0 | <0.001 | 0.806 | 0.258 |
BMI or PSA or Age | |||||||
Adjusted | 5 | 0.64 | 0.48–0.79 | 87.0 | <0.001 | 0.086 | 0.004 |
Not adjusted | 2 | 0.78 | 0.60–0.97 | 0.0 | 0.908 | – | – |
Note: HR, Hazard ratio; 95%CI, 95% confidence intervals; PCa, prostate cancer; PSA, prostate-specific antigen.