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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Transplantation. 2016 Sep;100(9):1907–1915. doi: 10.1097/TP.0000000000001290

Figure 1. Allogeneic hepatocytes elicit rapid rejection whether transplanted directly (intraportal) or indirectly (intrasplenic) to the liver microenvironment.

Figure 1

FVB/N (H-2q) hepatocytes were transplanted into untreated wild-type (WT; H-2b) recipients by intraportal injection (n=10) or by intrasplenic (n=15) injection. Graft rejection occurred promptly in both recipients transplanted directly to the liver by intraportal injection and those transplanted by conventional intrasplenic injection (MST=10 days, p=ns).