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. 2016 Jul 7;6:28711. doi: 10.1038/srep28711

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Copyright © 2016, Macmillan Publishers Limited

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(A) RT-QuIC reactions, seeded with brain tissue (10% v/w) from sCJD (MM1) patients (n = 5) in a dilution of 10⁻³ and (B) CSF from sCJD (MM1) patients (n = 14), were performed with different concentrations of doxycycline. The mean seeding response time course curves are shown.