6 v 0 |
Decrease in cytokine signaling |
Certain cytokines block adipogenesis |
19,20,67
|
Differential transcription factor regulation |
Cell cycle arrest, promotion of adipogenesis |
76, 77, 78, 79
|
48 v 6 |
IL signalling pathways |
Signalling through JAK/STAT |
67,100
|
Peroxisome & UnsatFA synthesis |
Fatty acid metabolism |
101 |
Prolactin receptor signalling |
Regulation of glucose/lipid & transporters |
95 |
Pathogenic E. coli |
Changes in cytoskeletal structures |
81, 82, 83
|
PPAR-γ pathway |
Nuclear receptor signalling |
74,80,91
|
NOTCH2,3,4 |
Signalling |
102,103
|
TGF-β |
Signalling |
104 |
Integrin |
Extracellular matricx |
85,105
|
96 v 48 |
PPAR-γ pathway |
PPAR signalling |
74,91
|
Focal adhesion/integrin |
Cell remodelling |
92 |
Insulin signalling |
Insulin responsiveness |
84 |
Leptin & adipokine |
Adipokine signaling |
67,98
|
Unsaturated fatty acid synthesis |
Fatty acid metabolism |
101 |
Glyoxlate, dicarboxylate, glycine, serine, threonine |
Precursors including for fatty acid biosynthesis |
|
NOTCH, TGFB, TRIAL, CTCF |
Cell signalling |
102,103
|
Citrate and TCA cycle |
Changes in energy metabolism |
97 |
Syndecan |
Link ECM to signalling pathways |
106 |
P53 pathway |
Cell cycle control |
107 |
192 v 96 |
WNT signalling |
Coupling signalling to transcription |
93,94
|
Insulin signalling |
Insulin responsiveness |
84 |
Glucose metabolism |
Changes in energy metabolism |
94 |
PPAR signalling |
PPAR signalling |
74,91
|
FOXM1 |
Multipl with DNA repair |
108 |
Peroxisome, FA metabolism |
Fatty acid metabolism |
101 |
IL5, ERK, ILK, P53 |
Cell signaling |
|
Porphyrin metabolism |
Linked to WNT signaling |
96 |
Regulation of pyruvate dehydrogenase, Citrate & TCA cycle |
Changes in energy metabolism |
97 |
Syndecan |
Link ECM to signalling pathways |
106 |
Branched chain amino acid |
Lipid biosynthesis |
109 |
384 v 192 |
Na independent glucose transporters |
Increased glucose & fructose uptake |
|
FRA Pathway |
Transcriptional regulations |
98,110
|
Integrin 4 |
Basement membrane structure |
105 |
NGF and Toll |
Cell signaling |
111 |
IGF1 Pathway |
Adipose regeneration |
112 |
Insulin signalling |
Insulin responsiveness |
84 |
Cardiaegf |
Calcium regulation |
113 |