Table 2. New EBMT criteria for SOS/VOD diagnosis in adults.

Classical SOS/VOD In the first 21 days after HSCT	Late onset SOS/VOD >21 Days after HSCT
Bilirubin ⩾2 mg/dL and two of the following criteria must be present:	Classical VOD/SOS beyond day 21
	OR
Painful hepatomegaly	Histologically proven SOS/VOD
Weight gain >5%	OR
Ascites	Two or more of the following criteria must be present:
	Bilirubin ⩾2 mg/dL (or 34 μmol/L)
	Painful hepatomegaly
	Weight gain>5%
	Ascites
	AND Hemodynamical or/and ultrasound evidence of SOS/VOD

Abbreviations: EBMT=European Society for Blood and Marrow Transplantation; SOS=sinusoidal obstruction syndrome; VOD=veno-occlusive disease.

These symptoms/signs should not be attributable to other causes.