TABLE 2.
Observed properties of the TDM series molecules identified in this study
Name (abbreviation) | Alternate name(s) | Producing strain(s) | Retention time (min) | UV-Vis abs max (nm)a | Mol formula | Mol wt (g/mol) | ESI-MS (m/z)b |
Mass accuracy (ppm) | |
---|---|---|---|---|---|---|---|---|---|
Observed | Calculated | ||||||||
W4.9 | WAC04657 | 4.9 | 260 | C18H24O7 | 352 | 353.1598 | 353.1600 | −0.6 | |
Dihydro-tetrodecamycin (dhTDM) | A5.4, G5.4 | S atroolivaceus, S. globisporus | 5.4 | 251 | C18H24O6 | 336 | 337.1651 | 337.1651 | 0 |
W5.9 | WAC04657 | 5.9 | 271 | C18H24O6 | 336 | 337.1664 | 337.1651 | 3.9 | |
W6.3 | WAC04657 | 6.3 | 243 | C18H22O5 | 318 | 341.1364 | 341.1365 | −0.3 | |
Tetrodecamycin (TDM) | A6.4, G6.4, W6.4 | WAC04657, S. atroolivaceus, S. globisporus | 6.4 | 271 | C18H22O6 | 334 | 335.1496 | 335.1495 | 0.3 |
13-Deoxy-tetrodecamycin (13-dTDM) | W8.0 | WAC04657 | 8.0 | 271 | C18H22O5 | 318 | 319.1548 | 319.1545 | 0.9 |
UV-Vis absorbance maximum (abs max) was recorded on an HPLC column in a solution of 40% aqueous acetonitrile–0.1% formic acid.
ESI, electrospray ionization.