FIG 5.

Susceptibility of WT and IFN-α/βR^−/− mice. (A) Survival curves for mice infected with DTMUV. Three- to 4-week-old female WT (n = 5) or IFN-α/βR^−/− mice (n = 7) were i.p. inoculated with 10⁶ PFU of DTMUV and monitored daily for 21 days. Survival differences were judged by the log-rank test. Statistically significant difference is indicated. **, P < 0.01. (B) Clinical symptoms developed in IFN-α/βR^−/− mice infected with DTMUV. The IFN-α/βR^−/− mice showed hind limb paralysis.