FIG 8.

Host factor modulation in nasopharyngeal tissues from FMDV carriers (C) and noncarriers (NC). Host factor mRNA measurements in LCM-derived samples of nasopharyngeal tissues were assigned to four strata, separating observations with greater than 10-fold up- or-downregulation from observations with less up- or downregulation. The color of the data points indicates if the proportion of up- or downregulation for each host factor and microanatomical region within the defined strata was higher in carriers (orange) or noncarriers (green). Noncarriers had a more consistent induction of the targets measured.