Table 2. Association between Perceived Stress and Atrial Fibrillation (N=25,530).
| AF Cases | Model 1* OR (95%CI) | P-value | Model 2† OR (95%CI) | P-value | |
|---|---|---|---|---|---|
| No Stress (PSS=0) | 452/6,501 | 1.0 | - | 1.0 | - |
| Low Stress (1≤ PSS ≤3) | 638/8,616 | 1.12 (0.99, 1.27) | 0.086 | 1.12 (0.98, 1.27) | 0.094 |
| Moderate Stress (4≤ PSS ≤5) | 442/4,978 | 1.35 (1.18, 1.55) | <0.0001 | 1.27 (1.11, 1.47) | 0.0007 |
| High Stress (PSS > 5) | 630/5,435 | 1.93 (1.70, 2.20) | <0.0001 | 1.60 (1.39, 1.84) | <0.0001 |
| PSS per 1-unit increase | 2,162/25,530 | 1.09 (1.08, 1.11) | <0.0001 | 1.06 (1.05, 1.09) | <0.0001 |
Adjusted for age, sex, race, education, income, and geographic region.
Adjusted for Model 1 covariates with the addition of systolic blood pressure, HDL cholesterol, total cholesterol, body mass index, smoking, diabetes, exercise, alcohol consumption, depression, antihypertensive medications, lipid-lowering therapies, left ventricular hypertrophy, and prior cardiovascular disease.
CI, confidence interval; HDL, high-density lipoprotein; OR, odds ratio; PSS, perceived stress scale.