Table 3. Subgroup Analysis (N=25,530)*.
| AF Cases | Model 1† OR (95%CI) | P-value | Model 2‡ OR (95%CI) | P-value | Interactionδ P-value | |
|---|---|---|---|---|---|---|
| Age | ||||||
| <65 years | 848/12,962 | 1.66 (1.43, 1.93) | <0.0001 | 1.37 (1.15, 1.62) | 0.0003 | 0.28 |
| ≥65 years | 1,314/12,568 | 1.68 (1.46, 1.93) | <0.0001 | 1.45 (1.25, 1.68) | <0.0001 | |
| Sex | ||||||
| Female | 1,145/13,860 | 1.71 (1.50, 1.95) | <0.0001 | 1.41 (1.23, 1.63) | <0.0001 | 0.22 |
| Male | 1,017/11,670 | 1.65 (1.40, 1.94) | <0.0001 | 1.42 (1.19, 1.70) | 0.0001 | |
| Race | ||||||
| Black | 774/10,373 | 1.68 (1.44, 1.97) | <0.0001 | 1.34 (1.13, 1.59) | 0.0008 | 0.49 |
| White | 1,388/15,157 | 1.70 (1.49, 1.95) | <0.0001 | 1.48 (1.28, 1.71) | <0.0001 | |
| Income | ||||||
| <$35,000 | 1,033/10,674 | 1.80 (1.57, 2.06) | <0.0001 | 1.48 (1.28, 1.73) | <0.0001 | 0.064 |
| ≥$35,000 | 1,129/14,856 | 1.53 (1.31, 1.79) | <0.0001 | 1.34 (1.13, 1.58) | 0.0006 | |
| Education | ||||||
| High school or less | 904/9,693 | 1.74 (1.50, 2.02) | <0.0001 | 1.38 (1.18, 1.63) | <0.0001 | 0.33 |
| Some college or more | 1,258/15,837 | 1.63 (1.41, 1.87) | <0.0001 | 1.43 (1.23, 1.66) | <0.0001 |
*
ORs are presented for high stress (PSS >5).
†
Adjusted for age, sex, race, education, income, and geographic region.
‡
Adjusted for Model 1 covariates with the addition of systolic blood pressure, HDL cholesterol, total cholesterol, body mass index, smoking, diabetes, exercise, alcohol consumption, depression, antihypertensive medications, lipid-lowering therapies, left ventricular hypertrophy, and prior cardiovascular disease.
δ
Interactions tested using Model 2.
CI, confidence interval; HDL, high-density lipoprotein; OR, odds ratio; PSS, perceived stress scale.