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. Author manuscript; available in PMC: 2016 Jul 7.
Published in final edited form as: Genet Med. 2014 Oct 23;17(6):476–484. doi: 10.1038/gim.2014.131

Table 4.

LS family history scores versus MMRD+/germline− family history scores by gene implicated

MMRpro PREMM1,2,6
Group Gene Implicated N Min Med Max p-value N Min Med Max p-value
LS MLH1 26 4.3 98.4 99.8 <0.0001 26 5.5 49.3 96.0 <0.0001
MMRD+/germline− hMLH1/hPMS2 31 0 6.9 87.3 31 5 5.6 45

LS MSH2 45 0.3 90.8 100.0 0.0812 45 0.1 36.7 100.0 0.0536
MMRD+/germline− hMSH2/hMSH6 13 0.1 15.8 100.0 13 5.0 12.1 91.8

LS MSH6 18 0.3 7.3 91.7 0.9406 18 5.0 8.1 65.0 0.5000
MMRD+/germline− hMSH6 5 0.0 11.1 74.5 5 5.0 7.1 10.5