Table 1.
Selected baseline patient and disease characteristics
| FAS population | |
|---|---|
| Age (years): median (range) | 64 (25–91) |
| Age (years): n (%) | |
| < 65 | 343 (52.4) |
| ≥ 65 | 311 (47.6) |
| BMI (Kg/m2) | 24 (14.1–49.1) |
| ECOG Performance Status: n (%) | |
| 0 | 200 (30.7) |
| 1 | 383 (58.7) |
| 2 | 60 (9.2) |
| 3 | 9 (1.4) |
| Missing | 2 |
| Site of Primary tumour: n (%) | |
| Colon | 445 (69.9) |
| Rectum | 186 (29.9) |
| Colon and rectum | 5 (0.2) |
| Missing | 18 |
| Timing of metastases: n (%) | |
| Synchronous | 416 (65.6) |
| Metachronous | 218 (34.4) |
| missing | 20 |
| Delay from initial diagnosis of metastases (months): median (range) | 31 (0.8–156.5) |
| Delay from initial diagnosis of metastases (months): n (%) | |
| < 18 | 134 (20.6) |
| ≥ 18 | 518 (79.4) |
| Missing | 2 |
| KRAS mutational status: n (%) | |
| Wild | 291 (46.8) |
| Mutated | 331 (53.2) |
| Missing | 32 |
| Initial dose of REG, mg/d, 3 w/4: n (%) | |
| 40 | 3 (0.5) |
| 80 | 39 (6) |
| 120 | 89 (13.6) |
| 160 | 522 (79.9) |
| Missing | 1 |