Table 4.
FAS Population n = 654 | Median OS | 6-month OS rate | |
Score equal to 0,1, 2, or 3 (high benefit from REG, n = 213) | 1 | 9.2 | 67 % |
Score equal to 4 or 5 (moderate benefit from REG, n = 256) | 1.78 (1.45–2.18) | 5.2 | 45 % |
Score equal to 6+ (low benefit from REG, n = 147) | 2.70 (2.13–3.42) | 2.5 | 26 % |
FAS-CORRECT Population n =440 | |||
Score equal to 0 or 1 (high benefit from REG, n = 185) | 1 | 8.7 | 64 % |
Score equal to 2 (moderate benefit from REG, n = 206) | 1.67 (1.34–2.09) | 5.5 | 46 % |
Score equal to 3 (low benefit from REG, n = 48) | 2.54 (1.79–3.60) | 3.4 | 35 % |
Relative weights of the variables found independently related to survival (see Table 3) were added to obtain a total score. This score ranged from 0 to 10, and was then reduced to obtain three categories of patients with significantly different risks of death