Table 1.
The relationship between GPX2 protein expression and ESCC patients’ clinicopathological characteristics
| Clinical features | Cases | GPX2+ | GPX2− | P value |
|---|---|---|---|---|
| Age | ||||
| ≤ 58 years | 83 | 70 | 13 | 0.539 |
| > 58 years | 78 | 62 | 16 | |
| Sex | ||||
| Male | 117 | 95 | 22 | 0.670 |
| Female | 44 | 37 | 7 | |
| Size | ||||
| ≤ 4.5 cm | 98 | 83 | 15 | 0.265 |
| > 4.5 cm | 63 | 49 | 14 | |
| Site | ||||
| Upper | 13 | 12 | 1 | 0.380 |
| Middle | 107 | 89 | 18 | |
| Below | 41 | 31 | 10 | |
| Gross morphology | ||||
| Medullary | 79 | 69 | 10 | 0.258 |
| Umbrella | 11 | 9 | 2 | |
| Ulcer | 54 | 40 | 14 | |
| Stenosis | 17 | 14 | 3 | |
| Histological grade | ||||
| I | 46 | 41 | 5 | <0.001 |
| II | 94 | 86 | 8 | |
| III | 21 | 5 | 16 | |
| TNM stages | ||||
| I~II | 86 | 75 | 11 | 0.118 |
| III | 73 | 55 | 18 | |
| IV | 2 | 2 | 0 | |
GPX2+: ESCC with GPX2-positive expression; GPX2−: ESCC with GPX2-negative expression
Histological grade: I, high differentiated ESCC; II, moderately differentiated ESCC; III, poorly differentiated ESCC