Table 2.
Infection characteristics
| Group 1 | Group 2 | Group 3 | P | |
|---|---|---|---|---|
| (n = 149) | (n = 91) | (n = 61) | ||
| Source of infection | 0.01 | |||
| Pulmonary | - | 44 (48) | 15 (25) | |
| Abdominal | - | 30 (33) | 29 (47) | |
| Urogenital | - | 8 (9) | 2 (3) | |
| Neurologic | - | 2 (2) | 2 (3) | |
| Soft tissue/bones | - | 7 (8) | 10 (17) | |
| Blood and catheter | - | 0 | 3 (5) | |
| Gram strain | 0.01 | |||
| Gram-negative | - | 30 (33) | 16 (26) | |
| Gram-positive | - | 27 (30) | 36 (59) | |
| Type of microorganism | 0.15 | |||
| Staphylococci | - | 15 (16) | 17 (28) | |
| Streptococci | - | 12 (13) | 19 (31) | |
| Enterobacteriaceae | - | 26 (29) | 15 (25) | |
| Pseudomonas | - | 4 (4) | 1 (2) | |
| Fungi | - | 12 (13) | 6 (10) | |
| Viral | - | 5 (5) | 3 (5) | |
| Biomarkers | ||||
| SIRS | 146 (98) | 90 (99) | 58 (95) | 0.94 |
| Septic shock | - | 12 (13) | 9 (15) | 0.78 |
| Temperature (°C) | 38.1 (1.5) | 38.3 (1.7) | 38.0 (1.5) | 0.94 |
| Heart rate (beats/minute) | 105 (29) | 109 (37) | 112 (39) | 0.15 |
| Respiratory rate (breaths/minute) | 28 (13) | 29 (17) | 29 (17) | 0.61 |
| WBC day 0 (109/L) | 12.4 (7.8) | 14.4 (12.9) | 13.9 (12.2) | 0.63 |
| WBC day 1 (109/L) | 11.7 (8.1) | 13.9 (13.1) | 13.4 (11.3) | 0.47 |
| WBC day 2 (109/L) | 12.1 (7.2) | 14.4 (9.8) | 14.8 (15.0) | 0.19 |
| CRP day 0 (mg/L) | 84 (109) | 163 (156) | 167 (161) | <0.001 |
| CRP day 1 (mg/L) | 88 (131) | 156 (156) | 197 (154) | <0.001 |
| CRP day 2 (mg/L) | 82 (141) | 131 (136) | 180 (172) | <0.001 |
| PCT day 0 (μg/L) | 0.65 (2.30) | 2.71 (9.88) | 4.13 (38.0) | <0.001 |
| ICIS day 0 | 3 (3) | 6 (5) | 6 (5) | <0.001 |
| ICIS day 1 | 3 (3) | 6 (4) | 6 (4) | <0.001 |
| ICIS day 2 | 4 (4) | 6 (4) | 6 (4) | <0.001 |
Numbers (percentage) or median (interquartile range), where appropriate. Group 1: no infection; Group 2: local infection without blood stream infection; Group3: blood stream infection. Abbreviations: CRP C-reactive protein, ICIS intensive care infection score, PCT procalcitonin, SIRS systemic inflammatory response syndrome, WBC white blood cells