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. Author manuscript; available in PMC: 2017 Jun 15.
Published in final edited form as: Bioorg Med Chem Lett. 2016 Feb 22;26(12):2965–2973. doi: 10.1016/j.bmcl.2016.02.061

Figure 5.

Figure 5

in vivo efficacies of novel FAAH inhibitors (Table1) in the mouse tail flick test. A–F shows tail flick latencies in the 52° C tail flick test following intraperitoneal injection of doses of novel FAAH inhibitors G shows summary data for all compounds where compound 1b shows the best in vivo potency. * p < 0.05, ** p < 0.01, *** p < 0.001 two way ANOVA with Bonferroni posthoc test.