. Author manuscript; available in PMC: 2017 Jun 15.

Published in final edited form as: Bioorg Med Chem Lett. 2016 Feb 22;26(12):2965–2973. doi: 10.1016/j.bmcl.2016.02.061

Table 3.


Compound	Parent	Y	W(−CHO₂)
1a	434.5 [M+H]⁺	113.1 [M+H3O]⁺	Not Found
2c	433.5 [M+H]⁺	94.1 [M+H]⁺	359.4 [M+2Na]⁺

m/z values for the parent and product ions of the aryl carbamate (1a) and urea (2c). HPLC/MS conditions are described in Experimental procedures. Under the conditions of the experiment phenol was detected primarily as an adduct (water), although the parent [M+H] ⁺ = 95.1 was present in trace amounts. The product ion m/z=359.4 was also detected in control extraction of incubation buffers containing only the piperidinyl scaffold. For 1a X is O; for 2c X is N.