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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Ann Neurol. 2016 Jan 13;79(3):419–427. doi: 10.1002/ana.24575

FIGURE 1.

FIGURE 1

Haplotype analysis of markers from chromosome 22q12.1–q12.3 in family (CMT105) with autosomal dominant Charcot–Marie–Tooth disease type 2 with pyramidal signs. The haplotype segregating with the disease is boxed. The markers are ordered from centromere (top) to telomere (bottom). Solid symbols denote affected individuals; open symbols denote unaffected individuals. Symbols with a question mark denote unknown phenotype. A diagonal line through a symbol denotes deceased individual. For the 6.6Mb linkage interval, individual III-4 defines the proximal boundary at D22S1154 and individuals III-13 and IV-4 define the distal boundary at D22S280.