Table 2.

Odds ratios (OR) with 95 % confidence intervals (CI) between lung cancer and categories of time-weighted average occupational social prestige for all lung cancers combined and major histological subtypes of lung cancer

Type of lung cancer/Social prestige category a	Cases [N]	Controls [N]	OR1 b (95 % CI)	OR2 c (95 % CI)	OR3 d (95 % CI)	OR4 e (95 % CI)
All lung cancers
High	2,215	4,592	1.0	1.0	1.0	1.0
Medium	3,980	4,854	1.67 (1.56–1.78)	1.39 (1.29–1.50)	1.37 (1.27–1.47)	1.23 (1.13–1.33)
Low	5,238	4,701	2.32 (2.17–2.48)	1.74 (1.61–1.87)	1.68 (1.55–1.81)	1.44 (1.32–1.57)
Squamous cell carcinoma
High	812	4,592	1.0	1.0	1.0	1.0
Medium	1,705	4,854	1.93 (1.76–2.12)	1.56 (1.41–1.73)	1.54 (1.39–1.71)	1.29 (1.15–1.45)
Low	2,358	4,701	2.85 (2.60–3.12)	2.08 (1.88–2.30)	2.03 (1.83–2.25)	1.58 (1.40–1.78)
Small cell carcinoma
High	324	4,592	1.0	1.0	1.0	1.0
Medium	638	4,854	1.89 (1.64–2.18)	1.48 (1.27–1.72)	1.44 (1.24–1.68)	1.29 (1.10–1.53)
Low	881	4,701	2.78 (2.42–3.19)	1.94 (1.67–2.24)	1.86 (1.60–2.16)	1.62 (1.37–1.92)
Adenocarcinoma
High	690	4,592	1.0	1.0	1.0	1.0
Medium	963	4,854	1.27 (1.14–1.42)	1.10 (0.98–1.24)	1.08 (0.96–1.21)	1.01 (0.89–1.15)
Low	1,165	4,701	1.64 (1.47–1.82)	1.28 (1.14–1.43)	1.22 (1.09–1.37)	1.13 (0.99–1.29)

a Categories for social prestige scores according to tertiles among control subjects: Low = 13- ≤ 35, Medium = >35- ≤ 45, and High = >45-78 points

b Odds ratios for model 1 are adjusted for study center and log(age)

c Odds ratios for model 2 are additionally adjusted for smoking status with time since quitting (2–7, 8–15, 16–25 or ≥ 26 years before interview/diagnosis, other types of tobacco only, non-smokers), and log(pack-years + 1)

d Odds ratios for model 3 are additionally adjusted for ever working in “List A” occupation

e Odds ratios for model 4 are additionally adjusted for highest education