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IC50 values, cytotoxicity rates and AL-I-DNA adduct accumulation in HK-2 cells
| Compound | Exposure (h) | IC50 (µM) | Compound (µM) | % decline in ATP/h | AL-I-DNA/(107 nucleotides/h) |
|---|---|---|---|---|---|
| AA-I | 24 | 52.53±6.36 | 5 | NA | 1.22±0.15 |
| 12.5 | 2.04±0.10 | 5.99±1.25 | |||
| 48 | 12.24±1.39 | 25 | 2.32±0.15 | 8.93±1.56 | |
| AL-I-NOH | 24 | 41.19±3.94 | 5 | NA | 2.16±0.17 |
| 48 | 21.34±2.46 | 12.5 | 0.71±0.22 | 2.89±0.15 | |
| 25 | 1.37±0.20 | 3.90±0.81 |
NA, not applicable.
