. Author manuscript; available in PMC: 2016 Jul 7.

Published in final edited form as: J Biomed Inform. 2015 Jan 13;54:106–113. doi: 10.1016/j.jbi.2015.01.001

Table 2.

Optimal log₂ ratio threshold determined for the 385 K array at every 720 K array log₂ ratio threshold value using CNV-ROC.

720 K gold standard log₂ ratio	All CNV types	Deletions	Duplications
0.20	0.30	0.30	0.25
0.25	0.30	0.30	0.25
0.30	0.30	0.35	0.30
0.35	0.35	0.40	0.30
0.40	0.35	0.40	0.35
0.45	0.40	0.45	0.35
0.50	0.50	0.50	0.40
0.55	0.50	0.50	0.45
0.60	0.50	0.50	0.50
0.65	0.50	0.50	0.65
0.70	0.50	0.50	0.65

The optimal log₂ ratio was determined for deletions, duplications, and a combination of both deletions and duplications. Overall, larger log₂ ratio threshold are more appropriate for duplications than for deletions. The larger range for duplications is due to smaller numbers of CNV duplications.