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. 2016 Mar 3;68(1):33–40. doi: 10.1097/FJC.0000000000000379

FIGURE 3.

FIGURE 3.

Comparative effects of EPA, fenofibrate, niacin, gemfibrozil, and vitamin E on human sdLDL (A), LDL (B), and VLDL (C) oxidation. All agents were tested at 10 μM. Data were collected after 1 hour (sdLDL and LDL) and 4 hours (VLDL) exposure to oxidative conditions. Values are mean ± SD (N = 3) and are expressed as molar equivalents of MDA. *P < 0.001 versus vehicle-treated control; †P < 0.001 versus fenofibrate, niacin, or gemfibrozil; ‡P < 0.001 versus vitamin E; §P < 0.05 versus vehicle-treated control (Student–Newman–Keuls multiple comparisons test; overall ANOVA—sdLDL data: P < 0.0001, F = 1268.1; LDL data: P < 0.0001, F = 132.38; VLDL data: P < 0.0001, F = 1031.4). ANOVA, analysis of variance; Fenofib, fenofibrate; Gemfib, gemfibrozil; MDA, malondialdehyde.