Table 1.
Main characteristics of studies included in this meta-analysis.
| First author | Year | Source of controls | Sample size case/control | Genotypes distribution (case/control) | HWE Y/N(p) | MAF | NOS score | Stratification | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 137G/C | GG | GC | CC | C | ||||||
| Chen | 2010 | PB | 190/210 | 111/145 | 71/59 | 8/6 | Y(1) | 0.169 | 8 | |
| Zhang | 2010 | PB | 423/384 | 313/279 | 105/91 | 5/14 | Y(0.062) | 0.155 | 8 | Subtypes of IS, Age, Sex |
| Li | 2011 | PB | 98/100 | 76/62 | 19/33 | 3/5 | Y(0.823) | 0.215 | 8 | |
| Wang | 2011 | PB | 218/218 | 174/146 | 42/66 | 2/6 | Y(0.652) | 0.179 | 8 | Subtypes of IS |
| Ren | 2012 | PB | 193/120 | 161/96 | 29/23 | 3/1 | Y(0.768) | 0.104 | 8 | |
| Wang | 2013 | PB | 291/226 | 240/180 | 46/43 | 5/3 | Y0.813) | 0.108 | 8 | |
| Wei | 2013 | PB | 153/114 | 91/85 | 54/25 | 8/4 | Y(0.223) | 0.145 | 7 | |
| 607C/A | CC | CA | AA | C | ||||||
| Zhang | 2010 | PB | 423/384 | 122/81 | 227/207 | 74/96 | Y(0.118) | 0.480 | 8 | Subtypes of IS, Age, Sex |
| Li | 2011 | PB | 98/100 | 25/23 | 55/56 | 18/21 | Y(0.228) | 0.510 | 8 | |
| Ren | 2012 | PB | 193/120 | 58/17 | 99/71 | 36/32 | N(0.027) | 0.438 | 8 | |
| Lu | 2013 | PB | 386/364 | 116/77 | 188/195 | 82/92 | Y(0.162) | 0.479 | 8 | Age, Sex |
| Wang | 2013 | PB | 291/226 | 91/50 | 147/108 | 53/68 | Y(0.566) | 0.460 | 8 | |
HWE, Hardy-Weinberg equilibrium; Y, yes (pH value of HWE > 0.05); N, no (p value of HWE < 0.05); MAF, minor allele frequency in control; NOS, Newcastle Ottawa Scale; PB, population-based controls; IS, ischemic stroke.