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. 2016 Apr 27;214(3):447–453. doi: 10.1093/infdis/jiw166

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© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — A, Phylogenetic, midpoint-rooted tree of study CC8 isolates, with USA300 isolates highlighted. A total of 56 isolates residing in the subclade within the gray box were phylogenetically identified as USA300 isolates. B, Detailed USA300 phylogenetic tree rooted on the isolate from P01, with a summary of metadata for each isolate. Person (P) numbers represent the study identifier of each individual from whom the sample was from, with gray boxes indicating pairs or clusters with presumptive epidemiological links. ±Red, resistant; yellow, intermediate; blue, susceptible. *Ciprofloxacin: red, S80Y and S84L; blue, S80F only; white, none identified; gray, not done. Staphylococcal cassette chromosome mec (SCCmec) IVa, Panton-Valentine leukocidin (PVL), arginine catabolic mobile element (ACME), staphylococcal pathogenicity island 5 (SAPI5): red, present; black, absent. ^Red, 4 mutations associated with the CAP5 locus were identified. Abbreviation: SNP, single-nucleotide polymorphism.