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. 2016 Jul 7;11(7):e0157670. doi: 10.1371/journal.pone.0157670

Fig 3. Transcriptome profiles of macrophage-like cells in BC tumors.

Fig 3

(a) Results of principal component analysis (PCA) for the subset of 1238 genes up- or downregulated in at least one comparison between MMTV-PyMT and BC-PyMT, HBCx-5, -24 or -34. The 15 samples, triplicates of MMTV-PyMT (green), BC-PyMT (orange), HBCx-5 (red), HBCx-24 (yellow) and HBCx-34 (blue), were projected oton the first three principal components, which accounted for ~58% of the total variability. Hierarchical clustering of the genes from the (b) “Immune system process” or (c) “Metabolic process” pathways from Gene Ontology analysis identified as significantly up- or downregulated in at least one comparison between BC-PyMT and HBCx-5, -24 and -34.